Molecular Structure:
Molecular Formula: C7H16O3
Molecular Weight: 148.2001
IUPAC Name: Diethoxymethoxyethane
Synonyms of Triethyl Orthoformate (CAS NO.122-51-0): 1,1',1'-(Methylidynetris(oxy))tris(ethane) ; 4-02-00-00025 (Beilstein Handbook Reference) ; AI3-24333 ; Aethon ; BRN 0605384 ; EINECS 204-550-4 ; Ethone ; Ethyl formate(ortho) ; Ethylester kyseliny orthomravenci ; Ethylester kyseliny orthomravenci [Czech] ; Methane, triethoxy- ; NSC 5289 ; Orthoformic acid ethyl ester (VAN) ; Orthoformic acid triethyl ester ; Orthoformic acid, ethyl ester ; Orthomravencan ethylnaty ; Orthomravencan ethylnaty [Czech] ; Triethoxymethane ; Triethyl orthoformate ; Triethylester kyseliny orthomravenci ; Triethylester kyseliny orthomravenci [Czech] ; Ethane, 1,1',1''-(methylidynetris(oxy))tris- ; Ethyl orthoformate [UN2524] [Flammable liquid] ; UN2524
CAS NO: 122-51-0
Classification Code: Skin / Eye Irritant
Melting point: −76 °C
Index of Refraction: 1.4
Molar Refractivity: 39.67 cm3
Molar Volume: 163.5 cm3
Surface Tension: 25.3 dyne/cm
Density: 0.906 g/cm3
Flash Point: 30 °C
Enthalpy of Vaporization: 36.4 kJ/mol
Boiling Point: 142.5 °C at 760 mmHg
Vapour Pressure: 6.99 mmHg at 25°C
Triethyl Orthoformate (CAS NO.122-51-0) is used to make other chemicals.
Triethyl Orthoformate (CAS NO.122-51-0) may be prepared from the reaction of sodium ethoxide and chloroform.
CHCl3 + 3 Na + 3 EtOH → HC(OEt)3 + 3/2 H2 + 3 NaCl
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | skin | > 10mL/kg (10mL/kg) | Food and Cosmetics Toxicology. Vol. 17, Pg. 917, 1979. | |
rabbit | LD50 | skin | 20mL/kg (20mL/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951. | |
rat | LCLo | inhalation | 4000ppm/8H (4000ppm) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951. | |
rat | LD50 | oral | 7060mg/kg (7060mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951. |
Hazard Codes of Triethyl Orthoformate (CAS NO.122-51-0): Xi
Risk Statements: 10-36/38
R10: Flammable.
R36/38: Irritating to eyes and skin.
Safety Statements: 16-26-37/39-36
S16: Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39: Wear suitable gloves and eye/face protection.
S36: Wear suitable protective clothing.
RIDADR: UN 2524 3/PG 3
WGK Germany: 1
RTECS: RM6475000
F: 21
HazardClass: 3
PackingGroup: III
HS Code: 29159080
European/International Regulations
European Labeling in Accordance with EC Directives